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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FREM3
All Species:
22.73
Human Site:
Y505
Identified Species:
71.43
UniProt:
P0C091
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C091
NP_001161707
2135
237764
Y505
L
A
A
G
R
V
V
Y
Q
H
D
G
S
N
T
Chimpanzee
Pan troglodytes
XP_517461
2289
255014
Y655
L
A
A
G
R
V
V
Y
Q
H
D
G
S
N
T
Rhesus Macaque
Macaca mulatta
XP_001092507
2276
253244
Y642
L
A
A
R
R
V
V
Y
Q
H
D
G
S
N
T
Dog
Lupus familis
XP_543127
3169
350410
Y516
L
A
A
G
Q
V
V
Y
H
H
D
D
K
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5H8B9
2123
234980
Y497
L
S
A
G
R
V
V
Y
Q
H
D
G
S
D
S
Rat
Rattus norvegicus
Q00657
2326
251891
F507
V
V
N
R
K
A
R
F
V
H
D
G
S
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417087
3168
351300
Y501
L
A
A
G
R
V
I
Y
Q
H
D
G
S
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796581
2335
258813
Y567
L
F
R
G
L
I
Y
Y
H
H
L
G
G
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
88.7
39.3
N.A.
68
20
N.A.
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.6
90.9
49.8
N.A.
80.1
35.7
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.2
P-Site Identity:
100
100
93.3
60
N.A.
80
26.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
P-Site Similarity:
100
100
93.3
73.3
N.A.
100
46.6
N.A.
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
63
75
0
0
13
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
88
13
0
25
13
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
38
0
% E
% Phe:
0
13
0
0
0
0
0
13
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
75
0
0
0
0
0
0
0
88
13
0
13
% G
% His:
0
0
0
0
0
0
0
0
25
100
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
13
13
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
88
0
0
0
13
0
0
0
0
0
13
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
13
0
0
0
0
0
0
0
0
0
0
38
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
63
0
0
0
0
0
0
% Q
% Arg:
0
0
13
25
63
0
13
0
0
0
0
0
0
0
0
% R
% Ser:
0
13
0
0
0
0
0
0
0
0
0
0
75
0
25
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
38
% T
% Val:
13
13
0
0
0
75
63
0
13
0
0
0
0
0
13
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
13
88
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _